The mTOR pathway in the control of protein synthesis.
نویسندگان
چکیده
Signaling through mammalian target of rapamycin (mTOR) is activated by amino acids, insulin, and growth factors, and impaired by nutrient or energy deficiency. mTOR plays key roles in cell physiology. mTOR regulates numerous components involved in protein synthesis, including initiation and elongation factors, and the biogenesis of ribosomes themselves.
منابع مشابه
The effect of 8 weeks endurance exercise on the content of total and phosphorylated AKT1, mTOR, P70S6K1 and 4E-BP1 in skeletal muscle FHL of rats with type 2 diabetes
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عنوان ژورنال:
- Physiology
دوره 21 شماره
صفحات -
تاریخ انتشار 2006